ABCA10

Across TCGA cell cohorts, ABCA10 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,770 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ABCA10-associated GO terms across cancer lineages are Negative regulation of non-canonical NF-kappaB signal transduction, Fibroblast migration, and Regulation of miRNA catabolic process. Each is linked with ABCA10 in more than 6 cancer types. Because this analysis shows association rather than direction, both ABCA10-to-partner and partner-to-ABCA10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of non-canonical NF-kappaB signal transduction grouped by ABCA10-low versus ABCA10-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCA10→partner) and Y-score (partner→ABCA10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Negative regulation of non-canonical NF-kappaB signal transduction →	+0.111	+1.658	<.001	<.001	3	7
URINARY_TRACT	Fibroblast migration →	+0.186	+1.343	<.001	.001	3	6
URINARY_TRACT	Regulation of miRNA catabolic process →	+0.204	+1.368	<.001	.001	3	6
CNS	Cytoplasmic translation →	+0.046	+0.527	<.001	<.001	3	6
LARGE_INTESTINE	Chiasma assembly →	+0.159	+0.217	<.001	.004	3	5
BREAST	Positive regulation of cytoplasmic translation →	+0.081	+0.337	.003	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,770 associations by consensus.

Negative regulation of non-canonical NF-kappaB signal transduction by ABCA10 expression — URINARY_TRACT

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