ABCA10

Across TCGA cell cohorts, ABCA10 mutation is significantly associated with the RNA expression of many other genes, with 848 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ABCA10-associated genes across cancer lineages are OR1L3, C1orf146, and TRMU. Each is linked with ABCA10 in more than 2 cancer types. Because this analysis shows association rather than direction, both ABCA10-to-partner and partner-to-ABCA10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR1L3 grouped by ABCA10-low versus ABCA10-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCA10→partner) and Y-score (partner→ABCA10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OR1L3 →	+0.029	+5.415	<.001	.004	3	3
STOMACH	C1orf146 →	+0.028	+3.432	.001	.008	3	2
LARGE_INTESTINE	TRMU →	+0.535	+3.321	.002	.003	3	2
LARGE_INTESTINE	TANGO6 →	+0.507	+2.389	.006	.006	3	2
LARGE_INTESTINE	UGDH →	+0.846	+3.321	.001	.003	3	2
LARGE_INTESTINE	LANCL1 →	+0.808	+2.389	.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 848 associations by consensus.

OR1L3 by ABCA10 expression — SKIN

Explore this box plot interactively →