Across TCGA patient cohorts, ABAT protein abundance is significantly associated with the RNA expression of many other genes, with 15,208 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ABAT-associated genes across cancer lineages are SLC1A2, SKA1, and YWHAZ. Each is linked with ABAT in more than 4 cancer types. Because this analysis shows association rather than direction, both ABAT-to-partner and partner-to-ABAT results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABAT→partner) and Y-score (partner→ABAT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SLC1A2 →	+1.242	+1.140	<.001	<.001	3	5
BRCA	SKA1 →	-1.041	-0.895	<.001	<.001	3	5
HNSC	YWHAZ →	-0.629	-0.447	.006	.004	3	5
UCEC	CDC6 →	-0.791	-0.549	.003	.002	3	5
LSCC	FANCI →	-0.760	-0.482	<.001	.003	3	5
COAD	UFD1 →	-0.389	-0.668	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,208 associations by consensus.

Exploration

ABAT survival (RNA) · tumor vs normal (RNA) · all ABAT data types