Across TCGA patient cohorts, ABAT mutation is significantly associated with the total protein of many other genes, with 19 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ABAT-associated genes across cancer lineages are MEK1, PR, and eEF2. Each is linked with ABAT in more than 1 cancer types. Because this analysis shows association rather than direction, both ABAT-to-partner and partner-to-ABAT results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABAT→partner) and Y-score (partner→ABAT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MEK1 →	+0.420	+3.169	.005	.018	3	2
UCEC	PR →	-0.206	-2.999	.047	.035	3	2
SKCM	eEF2 →	+0.302	+2.321	.040	.033	3	1
SKCM	PREX1 →	-0.367	-3.321	.012	.009	2	2
UCEC	14-3-3_beta →	-0.093	-2.973	.025	.035	3	1
UCEC	GAPDH →	+0.504	+1.700	.022	.042	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

Exploration

ABAT survival (RNA) · tumor vs normal (RNA) · all ABAT data types