Across TCGA cell cohorts, ABAT mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible ABAT-associated genes across cancer lineages are MAGEB5, RFPL3, and RHOXF2. Each is linked with ABAT in more than 1 cancer types. Because this analysis shows association rather than direction, both ABAT-to-partner and partner-to-ABAT results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABAT→partner) and Y-score (partner→ABAT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	MAGEB5 →	+0.033	+4.643	<.001	.008	3	1
SKIN	RFPL3 →	+0.048	+3.777	.004	.007	3	1
SKIN	RHOXF2 →	+0.083	+3.793	<.001	.007	3	1
LARGE_INTESTINE	OR10Q1 →	+0.112	+3.920	.001	.005	3	1
LARGE_INTESTINE	OR52H1 →	+0.025	+4.347	<.001	.001	3	1
LUNG_NSCLC_LUAD	TBATA →	+0.178	+3.544	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Exploration

ABAT survival (RNA) · tumor vs normal (RNA) · all ABAT data types