AATK

Across TCGA cell cohorts, AATK RNA expression is significantly associated with the go_rna of many other GO terms, with 4,726 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible AATK-associated GO terms across cancer lineages are Negative regulation of mRNA metabolic process, Regulation of syncytium formation by plasma membrane fusion, and Regulation of calcium ion transport into cytosol. Each is linked with AATK in more than 10 cancer types. Because this analysis shows association rather than direction, both AATK-to-partner and partner-to-AATK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of mRNA metabolic process grouped by AATK-low versus AATK-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AATK→partner) and Y-score (partner→AATK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Negative regulation of mRNA metabolic process →	+0.090	+1.781	<.001	<.001	3	11
BONE	Regulation of syncytium formation by plasma membrane fusion →	+0.095	+1.691	.001	<.001	3	10
LIVER	Regulation of calcium ion transport into cytosol →	-0.270	-1.592	<.001	<.001	3	9
BONE	Regulation of myoblast fusion →	+0.100	+1.788	.001	<.001	3	9
BONE	Positive regulation of DNA repair →	+0.102	+1.495	<.001	<.001	3	9
BONE	Transcription pausing by RNA polymerase II →	+0.136	+1.166	.001	.002	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,726 associations by consensus.

Negative regulation of mRNA metabolic process by AATK expression — LIVER

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