AATF

Across TCGA cell cohorts, AATF RNA expression is significantly associated with the RNA expression of many other genes, with 9,101 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible AATF-associated genes across cancer lineages are PSMD11, NLE1, and PSME3. Each is linked with AATF in more than 16 cancer types. Because this analysis shows association rather than direction, both AATF-to-partner and partner-to-AATF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AATF versus PSMD11 in BLOOD_Myeloma, with a Pearson correlation of 0.76.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AATF→partner) and Y-score (partner→AATF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	PSMD11 →	+1.079	+0.601	<.001	<.001	3	17
LUNG_NSCLC_LUSC	NLE1 →	+1.033	+1.350	<.001	<.001	3	17
URINARY_TRACT	PSME3 →	+1.027	+0.947	<.001	<.001	3	16
OVARY	TAF15 →	+1.000	+1.104	<.001	<.001	3	16
URINARY_TRACT	PSMC5 →	+0.843	+0.756	<.001	<.001	3	16
BONE	PIGW →	+1.489	+0.939	<.001	<.001	2	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,101 associations by consensus.

AATF vs PSMD11 — BLOOD_Myeloma

Explore this scatter interactively →