AASDHPPT

Across TCGA patient cohorts, AASDHPPT mutation is significantly associated with the RNA expression of many other genes, with 354 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AASDHPPT-associated genes across cancer lineages are RNA5SP369, PLCE1P1, and MIR378E. Each is linked with AASDHPPT in more than 2 cancer types. Because this analysis shows association rather than direction, both AASDHPPT-to-partner and partner-to-AASDHPPT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP369 grouped by AASDHPPT-low versus AASDHPPT-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AASDHPPT→partner) and Y-score (partner→AASDHPPT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNA5SP369 →	+0.669	+5.539	<.001	.004	3	3
LUAD	PLCE1P1 →	+0.136	+6.339	<.001	<.001	3	2
UCEC	MIR378E →	+0.201	+2.930	<.001	.001	3	2
SKCM	PRELID1P2 →	+0.398	+5.624	<.001	.002	3	2
SKCM	MIR1228 →	+0.391	+6.810	<.001	<.001	3	2
UCEC	RN7SL354P →	+0.171	+1.608	.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 354 associations by consensus.

RNA5SP369 by AASDHPPT expression — CESC

Explore this box plot interactively →