AASDHPPT

Across TCGA cell cohorts, AASDHPPT RNA expression is significantly associated with the go_rna of many other GO terms, with 4,419 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible AASDHPPT-associated GO terms across cancer lineages are 10-formyltetrahydrofolate metabolic process, Folic acid-containing compound catabolic process, and Pyruvate decarboxylation to acetyl-CoA. Each is linked with AASDHPPT in more than 17 cancer types. Because this analysis shows association rather than direction, both AASDHPPT-to-partner and partner-to-AASDHPPT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 10-formyltetrahydrofolate metabolic process grouped by AASDHPPT-low versus AASDHPPT-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AASDHPPT→partner) and Y-score (partner→AASDHPPT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	10-formyltetrahydrofolate metabolic process →	+0.240	+1.038	<.001	<.001	3	18
OVARY	Folic acid-containing compound catabolic process →	+0.212	+0.826	<.001	.001	3	16
PANCREAS	Pyruvate decarboxylation to acetyl-CoA →	+0.154	+0.802	<.001	<.001	3	16
OVARY	Pteridine-containing compound catabolic process →	+0.212	+0.826	<.001	.001	3	16
URINARY_TRACT	Platelet activating factor catabolic process →	+0.209	+0.923	<.001	.002	3	15
URINARY_TRACT	Ether catabolic process →	+0.209	+0.923	<.001	.002	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,419 associations by consensus.

10-formyltetrahydrofolate metabolic process by AASDHPPT expression — URINARY_TRACT

Explore this box plot interactively →