AARSD1

Across TCGA cell cohorts, AARSD1 mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible AARSD1-associated genes across cancer lineages are OR11H1, PRAC1, and OR4K2. Each is linked with AARSD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both AARSD1-to-partner and partner-to-AARSD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR11H1 grouped by AARSD1-low versus AARSD1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AARSD1→partner) and Y-score (partner→AARSD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR11H1 →	+0.068	+4.201	<.001	.001	3	1
BLOOD_Leukemia	PRAC1 →	+0.587	+3.884	.003	.003	3	1
BLOOD_Leukemia	OR4K2 →	+0.020	+3.969	<.001	.009	3	1
BLOOD_Leukemia	BPIFB6 →	+0.031	+3.969	<.001	.009	3	1
BLOOD_Leukemia	BPIFB3 →	+0.106	+3.289	<.001	.009	3	1
BLOOD_Leukemia	OR11G2 →	+0.197	+3.922	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

OR11H1 by AARSD1 expression — BLOOD_Leukemia

Explore this box plot interactively →