AAR2

Across TCGA patient cohorts, AAR2 protein abundance is significantly associated with the RNA expression of many other genes, with 10,425 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible AAR2-associated genes across cancer lineages are CTNNBL1, DSN1, and RBL1. Each is linked with AAR2 in more than 6 cancer types. Because this analysis shows association rather than direction, both AAR2-to-partner and partner-to-AAR2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AAR2 versus CTNNBL1 in OV, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AAR2→partner) and Y-score (partner→AAR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CTNNBL1 →	+0.691	+0.483	<.001	<.001	3	7
LUAD	DSN1 →	+0.787	+0.232	<.001	<.001	3	7
LUAD	RBL1 →	+0.667	+0.233	<.001	<.001	3	7
LUAD	CSTF1 →	+0.448	+0.212	<.001	<.001	3	6
COAD	RAE1 →	+0.707	+0.271	<.001	<.001	3	6
BRCA	MRGBP →	+0.530	+0.295	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,425 associations by consensus.

AAR2 vs CTNNBL1 — OV

Explore this scatter interactively →