AAR2

Across TCGA cell cohorts, AAR2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,325 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible AAR2-associated GO terms across cancer lineages are DNA-templated transcription initiation, Spliceosomal tri-snRNP complex assembly, and Regulation of DNA-templated transcription initiation. Each is linked with AAR2 in more than 10 cancer types. Because this analysis shows association rather than direction, both AAR2-to-partner and partner-to-AAR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated transcription initiation grouped by AAR2-low versus AAR2-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AAR2→partner) and Y-score (partner→AAR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	DNA-templated transcription initiation →	+0.063	+0.708	<.001	<.001	3	11
SKIN	Spliceosomal tri-snRNP complex assembly →	+0.098	+0.664	<.001	<.001	3	11
SOFT_TISSUE	Regulation of DNA-templated transcription initiation →	+0.085	+0.764	<.001	<.001	3	10
STOMACH	Regulation by virus of viral protein levels in host cell →	+0.219	+1.151	<.001	<.001	3	10
BLOOD_Myeloma	Nucleocytoplasmic transport →	+0.072	+0.872	.001	<.001	3	10
SKIN	Regulation of transcription elongation by RNA polymerase II →	+0.070	+0.650	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,325 associations by consensus.

DNA-templated transcription initiation by AAR2 expression — BLOOD_Lymphoma

Explore this box plot interactively →