AAMDC

Across TCGA cell cohorts, AAMDC RNA expression is significantly associated with the go_rna of many other GO terms, with 2,949 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible AAMDC-associated GO terms across cancer lineages are Mitochondrial large ribosomal subunit assembly, Ribosome assembly, and Ribosomal small subunit biogenesis. Each is linked with AAMDC in more than 11 cancer types. Because this analysis shows association rather than direction, both AAMDC-to-partner and partner-to-AAMDC results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial large ribosomal subunit assembly grouped by AAMDC-low versus AAMDC-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AAMDC→partner) and Y-score (partner→AAMDC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Mitochondrial large ribosomal subunit assembly →	-0.104	-1.101	.003	.008	2	12
BONE	Ribosome assembly →	-0.096	-0.887	.002	.002	3	11
LUNG_SCLC	Ribosomal small subunit biogenesis →	-0.100	-0.790	.001	.003	3	11
LUNG_SCLC	Macromolecule methylation →	-0.055	-0.942	<.001	.001	3	11
LIVER	Regulation of metallopeptidase activity →	+0.200	+1.137	.007	.001	3	10
BONE	rRNA modification →	-0.109	-0.939	.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,949 associations by consensus.

Mitochondrial large ribosomal subunit assembly by AAMDC expression — URINARY_TRACT

Explore this box plot interactively →