AAGAB

Across TCGA patient cohorts, AAGAB RNA expression is significantly associated with the protein abundance of many other proteins, with 14,787 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible AAGAB-associated proteins across cancer lineages are AKAP13_S983, ATXN2L, and ZFAND6. Each is linked with AAGAB in more than 6 cancer types. Because this analysis shows association rather than direction, both AAGAB-to-partner and partner-to-AAGAB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AAGAB versus AKAP13_S983 in PDAC, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AAGAB→partner) and Y-score (partner→AAGAB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	AKAP13_S983 →	+0.708	+0.315	<.001	<.001	3	7
LSCC	ATXN2L →	+0.278	+0.539	<.001	<.001	3	6
OV	ZFAND6 →	+0.446	+0.375	<.001	<.001	3	6
BRCA	USP8 →	+0.184	+0.428	<.001	<.001	3	5
COAD	RTF1 →	+0.275	+0.448	.002	.009	2	6
HNSC	SMAD3 →	+0.349	+0.572	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,787 associations by consensus.

AAGAB vs AKAP13_S983 — PDAC

Explore this scatter interactively →