AAGAB

Across TCGA patient cohorts, AAGAB protein abundance is significantly associated with the RNA expression of many other genes, with 16,909 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible AAGAB-associated genes across cancer lineages are CIAO2A, CCNB2, and LEO1. Each is linked with AAGAB in more than 6 cancer types. Because this analysis shows association rather than direction, both AAGAB-to-partner and partner-to-AAGAB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AAGAB versus CIAO2A in OV, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AAGAB→partner) and Y-score (partner→AAGAB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CIAO2A →	+0.592	+0.297	.001	.001	3	7
OV	CCNB2 →	+1.131	+0.355	<.001	<.001	3	6
COAD	LEO1 →	+0.563	+0.277	.001	.004	3	6
COAD	PDIA3 →	+0.542	+0.341	.001	<.001	3	6
CCRCC	CSDC2 →	-1.436	-0.264	<.001	<.001	3	6
UCEC	KPNA2 →	+0.628	+0.244	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,909 associations by consensus.

AAGAB vs CIAO2A — OV

Explore this scatter interactively →