AAGAB

Across TCGA cell cohorts, AAGAB RNA expression is significantly associated with the go_rna of many other GO terms, with 3,615 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible AAGAB-associated GO terms across cancer lineages are Regulation of heterochromatin organization, Regulation of cell cycle checkpoint, and Ubiquitin-dependent protein catabolic process via the N-end rule pathway. Each is linked with AAGAB in more than 12 cancer types. Because this analysis shows association rather than direction, both AAGAB-to-partner and partner-to-AAGAB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of heterochromatin organization grouped by AAGAB-low versus AAGAB-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AAGAB→partner) and Y-score (partner→AAGAB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of heterochromatin organization →	+0.080	+0.703	<.001	<.001	3	13
OESOPHAGUS	Regulation of cell cycle checkpoint →	+0.125	+0.626	.008	.007	3	12
BLOOD_Leukemia	Ubiquitin-dependent protein catabolic process via the N-end rule pathway →	+0.082	+0.802	<.001	<.001	3	11
BLOOD_Myeloma	Establishment of protein localization to organelle →	+0.058	+0.839	<.001	<.001	3	11
CNS	Endosomal transport →	+0.048	+0.865	<.001	<.001	3	10
OESOPHAGUS	Regulation of sister chromatid segregation →	+0.106	+0.535	.002	.007	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,615 associations by consensus.

Regulation of heterochromatin organization by AAGAB expression — OVARY

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