AADACP1

Across TCGA pan-cancer cohorts, AADACP1 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of AADACP1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where AADACP1 RNA is repressed in tumor relative to normal tissue. In most cancer types AADACP1 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

THCA, KICH, and BRCA are the cancer types where AADACP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in AADACP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Female	II,III,IV	−2.348	<.001	11	view →
KICH	Male	IV	−0.340	<.001	10	view →
BRCA	All	III,IV	−0.570	<.001	6	view →
HNSC	Male	All	+0.965	.002	5	view →
KIRP	All	All	−0.090	<.001	5	view →
LUSC	All	All	+0.696	.002	4	view →
LUAD	All	All	−0.375	.019	3	view →
LIHC	Female	All	−0.633	.031	2	view →
PRAD	All	All	−0.104	.003	2	view →
LUSC	Male	III,IV	−0.805	.008	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 9 lineages.

AADACP1–THCA

Open the THCA breakdown →