Across TCGA patient cohorts, AADACL4 mutation is significantly associated with the RNA expression of many other genes, with 793 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AADACL4-associated genes across cancer lineages are LINC02794, OR9Q2, and RNA5SP367. Each is linked with AADACL4 in more than 2 cancer types. Because this analysis shows association rather than direction, both AADACL4-to-partner and partner-to-AADACL4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AADACL4→partner) and Y-score (partner→AADACL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LGG	LINC02794 →	+0.063	+4.711	<.001	.003	3	3
COAD	OR9Q2 →	+0.035	+4.136	<.001	.008	3	3
BLCA	RNA5SP367 →	+0.391	+5.038	<.001	.009	3	3
BRCA	MIR3648-2 →	+0.134	+7.473	<.001	.007	3	2
UCEC	MRM3 →	+0.467	+3.480	.003	.002	3	2
UCEC	NCAPH2 →	+0.485	+2.700	.005	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 793 associations by consensus.

Exploration

AADACL4 survival (RNA) · tumor vs normal (RNA) · all AADACL4 data types