Across TCGA patient cohorts, AADACL2 mutation is significantly associated with the RNA expression of many other genes, with 2,331 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AADACL2-associated genes across cancer lineages are RNU6-1292P, ANKRD60, and NANOGP6. Each is linked with AADACL2 in more than 2 cancer types. Because this analysis shows association rather than direction, both AADACL2-to-partner and partner-to-AADACL2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AADACL2→partner) and Y-score (partner→AADACL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNU6-1292P →	+0.289	+5.837	<.001	.001	3	3
CESC	ANKRD60 →	+0.031	+4.669	.003	.007	3	2
LUSC	NANOGP6 →	+0.205	+4.862	.002	<.001	3	2
CESC	VDAC1P9 →	+0.083	+4.455	<.001	.005	3	2
SKCM	MYO19 →	+0.444	+3.119	.002	<.001	3	2
UCEC	PIGW →	+0.475	+2.212	.003	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,331 associations by consensus.

Exploration

AADACL2 survival (RNA) · tumor vs normal (RNA) · all AADACL2 data types