Across TCGA cell cohorts, AADACL2 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible AADACL2-associated genes across cancer lineages are SH3GL2, TAFA1, and KRTAP10-2. Each is linked with AADACL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both AADACL2-to-partner and partner-to-AADACL2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AADACL2→partner) and Y-score (partner→AADACL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SH3GL2 →	+1.643	+3.474	<.001	.003	3	1
LARGE_INTESTINE	TAFA1 →	+0.205	+2.688	.004	.008	3	1
LARGE_INTESTINE	KRTAP10-2 →	+0.047	+3.257	<.001	.001	3	1
LARGE_INTESTINE	C16orf96 →	+0.461	+3.743	.005	.001	3	1
SKIN	HES5 →	+0.047	+4.155	.003	.003	3	1
SKIN	KRTAP4-2 →	+0.028	+4.437	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

AADACL2 survival (RNA) · tumor vs normal (RNA) · all AADACL2 data types