AACSP1

Across TCGA patient cohorts, AACSP1 mutation is significantly associated with the immune_cell of many other genes, with 10 significant associations in total. COAD shows the largest number of these associations.

The most reproducible AACSP1-associated genes across cancer lineages are B-cells, CD4+ memory T-cells, and CD8+ T-cells. Each is linked with AACSP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both AACSP1-to-partner and partner-to-AACSP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, B-cells grouped by AACSP1-low versus AACSP1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AACSP1→partner) and Y-score (partner→AACSP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	B-cells →	+0.056	+3.993	.003	.005	3	2
UCEC	CD4+ memory T-cells →	+0.031	+1.939	.002	.044	3	2
COAD	CD8+ T-cells →	+0.047	+5.557	<.001	.001	3	1
COAD	CD8+ Tcm →	+0.078	+5.332	<.001	.002	3	1
COAD	Astrocytes →	+0.053	+2.692	.008	.048	3	1
COAD	Macrophages →	+0.049	+3.703	<.001	.011	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

B-cells by AACSP1 expression — COAD

Explore this box plot interactively →