A4GALT

Across TCGA cell cohorts, A4GALT mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. CNS shows the largest number of these associations.

The most reproducible A4GALT-associated genes across cancer lineages are GFRA4, AQP12A, and DUSP29. Each is linked with A4GALT in more than 1 cancer types. Because this analysis shows association rather than direction, both A4GALT-to-partner and partner-to-A4GALT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GFRA4 grouped by A4GALT-low versus A4GALT-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (A4GALT→partner) and Y-score (partner→A4GALT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	GFRA4 →	+0.022	+5.754	<.001	.002	3	1
CNS	AQP12A →	+0.040	+4.981	<.001	.008	3	1
CNS	DUSP29 →	+0.032	+5.754	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

GFRA4 by A4GALT expression — CNS

Explore this box plot interactively →