A3GALT2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, A3GALT2 mutation is significantly associated with the RNA expression of many other genes, with 313 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible A3GALT2-associated genes across cancer lineages are GYS2, ST8SIA3, and CST9L. Each is linked with A3GALT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both A3GALT2-to-partner and partner-to-A3GALT2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (A3GALT2→partner) and Y-score (partner→A3GALT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OESOPHAGUSGYS2 →+0.086+4.017<.001.00731
OESOPHAGUSST8SIA3 →+0.042+4.392.001.00331
SKINCST9L →+0.039+4.415<.001.00731
SKINSLURP1 →+0.726+4.273<.001.00631
LUNG_NSCLC_LUADIQCF3 →+0.049+5.228<.001.00531
LUNG_NSCLC_LUADKRTAP19-3 →+0.132+5.228<.001.00531
Each partner links to its Q-omics profile. Showing the 6 strongest of 313 associations by consensus.

Exploration