A1BG

Across TCGA patient cohorts, A1BG mutation is significantly associated with the total protein of many other genes, with 10 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible A1BG-associated genes across cancer lineages are Caspase-7-cleavedD198, MEK1, and PEA-15. Each is linked with A1BG in more than 2 cancer types. Because this analysis shows association rather than direction, both A1BG-to-partner and partner-to-A1BG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by A1BG-low versus A1BG-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (A1BG→partner) and Y-score (partner→A1BG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Caspase-7-cleavedD198 →	+0.776	+3.708	.019	<.001	3	3
UCEC	MEK1 →	+0.344	+2.000	.037	.032	3	2
UCEC	PEA-15 →	+0.178	+2.000	.036	.032	3	2
UCEC	p62 Lck ligand →	+0.440	+3.331	.002	.005	3	1
UCEC	PDK1_pS241 →	+0.169	+3.321	.027	.010	3	1
UCEC	XBP1 →	-0.175	-3.321	.006	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Caspase-7-cleavedD198 by A1BG expression — COAD

Explore this box plot interactively →