A1BG

Across TCGA cell cohorts, A1BG mutation is significantly associated with the drug of many other genes, with 24 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible A1BG-associated genes across cancer lineages are Wee1 Inhibitor, PF-562271, and Embelin. Each is linked with A1BG in more than 1 cancer types. Because this analysis shows association rather than direction, both A1BG-to-partner and partner-to-A1BG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Wee1 Inhibitor grouped by A1BG-low versus A1BG-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (A1BG→partner) and Y-score (partner→A1BG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Wee1 Inhibitor →	+0.528	+2.871	.035	.021	3	1
LARGE_INTESTINE	PF-562271 →	+0.459	+2.807	.030	.040	3	1
LARGE_INTESTINE	Embelin →	+0.460	+2.807	.031	.040	3	1
LARGE_INTESTINE	GSK2276186C →	+0.467	+2.871	.033	.021	3	1
LARGE_INTESTINE	Ipatasertib →	+0.510	+2.871	.048	.021	3	1
LARGE_INTESTINE	Tipifarnib →	+0.891	+2.807	.021	.040	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

Wee1 Inhibitor by A1BG expression — LARGE_INTESTINE

Explore this box plot interactively →