N23918-95-7

Across CCLE and GDSC cell-line panels, response to N23918-95-7 is significantly associated with the pathway activity of multiple pathways, with LUNG_NSCLC_LUSC cell lines showing a particularly strong set of associations.

The most reproducible N23918-95-7 response-associated pathways across cancer lineages are UDP metabolic process, Pyrimidine ribonucleoside diphosphate metabolic process, and Fucose transmembrane transport, each associated with drug response in up to 9 lineages. Since the analysis identifies associations rather than directional relationships, both response-to-biomarker and biomarker-to-response views are provided.

Each biomarker is linked to its corresponding Q-omics profile. The scatter plot shows the strongest observed association, N23918-95-7 response versus UDP metabolic process pathway activity in LUNG_NSCLC_LUSC (Pearson r = 0.50).

Pathway activity biomarkers of N23918-95-7 response

Ranked by combined sampling and lineage consensus. X-score (response→biomarker) and Y-score (biomarker→response) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner pathway	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	UDP metabolic process →	+0.081	+0.439	.010	.004	3	8
LUNG_NSCLC_LUSC	Pyrimidine ribonucleoside diphosphate metabolic process →	+0.081	+0.439	.010	.004	3	8
BLOOD_Myeloma	Fucose transmembrane transport →	-1.130	-0.217	.038	.045	3	8
BREAST	Mitochondrial protein processing →	+0.095	+0.312	.002	.003	3	8
UPPER_AERODIGESTIVE_TRACT	Viral latency →	-0.137	-0.314	.017	.029	3	7
BONE	Negative regulation of endothelial cell differentiation →	-0.211	-0.365	.020	.030	2	8

Each biomarker links to its Q-omics profile. Showing the 6 strongest associations by consensus.

N23918-95-7 response vs UDP metabolic process — LUNG_NSCLC_LUSC

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